Inactivated Smallpox Vaccine: Immunogenicity of Inactivated Intracellular and Extracellular Vaccinia Virus

Immunogenicity of Concentrated and Purified Inactivated Avian Influenza Vaccine Formulation

Avian influenza (AI) H9N2 is a low pathogenic virus subtype belonging to Orthomyxoviridae family. Given the prevalence of this subtype as an infectious agent in poultry industry, special attention has been always directed toward the development of vaccine production against this infection. The vaccine of this infection is produced by killing the virus and using a mixture of inactivated antigen ...

Inactivated African Horse Sickness Virus Cell Culture Vaccine

Safety and immunogenicity of trivalent inactivated influenza vaccine in infants.

BACKGROUND Trivalent inactivated influenza vaccine (TIV) is not licensed for use in infants <6 months old, the group with the highest influenza hospitalization rates among children. METHODS In this prospective, open-label study, 2 doses of TIV were administered to healthy infants aged 10-22 weeks. Adverse reactions were assessed, and hemagglutination inhibition (HAI) antibody titers were dete...

Appendix B. —Safety and Efficacy of Inactivated Influenza Vaccine Description of Inactivated Influenza Virus Vaccine

Influenza vaccines can be categorized in two basic groups—live, which contain small amounts of live, attenuated (weakened) influenza viruses, and inactivated, which contain either whole influenza viruses or subunits of viruses. Only inactivated influenza viruses are licensed for general use in the United States; therefore, this discussion of vaccine safety and efficacy pertains exclusively to i...

The potency, toxicity and immunogenicity of glutaraldehyde inactivated pertussis vaccine

Whole cell pertussis vaccine was prepared by inactivation of Bordetella pertussis organisms with glutaraldehyde under optimal conditions (0.05% glutaraldehyde at room temperature for 10 minutes). This glutaraldehyde inactivated pertussis vaccine-1 (GIPV-1) was compared to the routinely produced heat inactivated (56°C for 30 minutes) pertussis vaccine (HIPV) for potency, toxicity and immunogenic...